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Safety and early outcomes of simultaneous bilateral TKA in patients with BMI > 40: A retrospective comparative study

SICOT-J -

SICOT J. 2025;11:24. doi: 10.1051/sicotj/2025019. Epub 2025 Apr 14.

ABSTRACT

INTRODUCTION: Simultaneous bilateral total knee arthroplasties (SBTKA) are common in Asia, but surgeons may have a body mass index (BMI) threshold for performing these procedures. However, no guidelines regarding patient weight and SBTKA exist in the literature. We hypothesized that SBTKA can be performed safely and efficiently for morbidly obese patients. We aimed to compare 1) the rate of complications within one year after surgery, 2) operative time, blood loss, and length of stay, and 3) clinical outcomes at one year after SBTKA in patients with BMI < 30 versus 30 < BMI < 40 and BMI > 40.

METHODS: In this retrospective comparative matched (age, ASA score) study, we evaluated 113 patients who underwent SBTKA (posterior stabilized cemented TKA), between 2019 and 2022. The patient population was grouped based on their BMI: BMI < 30 (33 patients), 30 < BMI < 40 (43 patients), and BMI > 40 (37 patients). A complication was defined as an event that could be classified as a grade > 3 according to the Clavien-Dindo classification within one year of surgery. Data on complication rate, operation time, blood loss, and preoperative and post-operative function KSS at one year were compared.

RESULTS: No significant difference in the occurrence of early complications between the three groups was observed. One patient was readmitted for periprosthetic fracture in the BMI < 30 group. There was no significant difference in operative time, blood loss, and KSS score at one year between the three groups. A significant functional improvement was observed in all three groups at the one-year follow-up.

DISCUSSION: This study suggests that SBTKA in patients with a BMI > 40 is safe, with no increased complications, similar surgical time, and blood loss. Significant functional improvement was observed at one year postoperatively. While promising, further multi-center studies are needed to confirm these findings and evaluate long-term outcomes.

PMID:40228109 | PMC:PMC11996129 | DOI:10.1051/sicotj/2025019

Changes in bone density, microarchitecture, and biomechanical properties after plate removal in surgically treated distal radius fractures: a prospective study

International Orthopaedics -

Int Orthop. 2025 Apr 14. doi: 10.1007/s00264-025-06529-w. Online ahead of print.

ABSTRACT

PURPOSE: Removal of volar locking plates after healing of a distal radius fracture is becoming increasingly common. However, it is unclear how the fracture healing proceeds and which defects remain. The aim of this study was to assess changes in bone microarchitecture and biomechanical properties in surgically treated radius fracture after volar locking plate removal.

METHODS: Twelve patients were recruited after undergoing plate removal. High Resolution Quantitative Computed Tomography (HR-pQCT) was used to perform scans of the fractured and contralateral distal radius on average one (M1) and 16 months (M2) after plate removal. Parameters measured were cortical- (Dcomp), trabecular- (Dtrab) and total bone density (D100), as well as cortical thickness (Ct.Th). Axial bone stiffness (FE.Kaxial) was determined through linear micro-finite element analysis (µFEA).

RESULTS: At M1, no significant differences between fractured and contralateral side were detected except for Dcomp. At the fractured side, all parameters except for Dtrab increased significantly between M1 and M2. At M2, Ct.Th and FE.Kaxial were significantly higher at the fractured side compared to the contralateral side, but Dcomp remained significantly lower. Qualitatively, closure of the screw holes was observed between M1 and M2, while large trabecular defects remained.

CONCLUSION: Bone (re)modeling at the distal radius is an ongoing process even after plate removal and leads to a partial exaggeration of the bone properties relative to the intact contralateral side. It seems that the bone regains its biomechanical competence by closing screw holes and increasing cortical thickness, which compensates for trabecular defects that cannot be repaired.

LEVEL OF EVIDENCE: III.

PMID:40227373 | DOI:10.1007/s00264-025-06529-w

Arthroscopic cystectomy and open surgery for the treatment of popliteal cysts: a retrospective clinical cohort study

International Orthopaedics -

Int Orthop. 2025 Apr 14. doi: 10.1007/s00264-025-06527-y. Online ahead of print.

ABSTRACT

PURPOSE: To compare the clinical effects of arthroscopic cystectomy and open surgery for the treatment of popliteal cysts, in order to provide clinical basis for the selection of surgical plan for popliteal cyst.

METHODS: A retrospective study was conducted on the clinical data of 153 patients diagnosed with popliteal cysts from January 2020 to December 2022. Among them, 77 patients underwent arthroscopic cystectomy as the observation group, and 76 patients underwent open surgery as the control group. Compared the surgical related indicators, Rauschening and Lindgren grade, Lysholm and VAS scores between two groups. Follow up on postoperative complications and cyst recurrence.

RESULTS: The observation group had a smaller incision length (P < 0.01), less intraoperative bleeding (P < 0.05), and shorter hospitalization time than the control group (P < 0.01), but longer surgical time (P < 0.05). Both groups of patients showed significant improvement in Rauschening and Lindgren grade, Lysholm and VAS scores after surgery, with the observation group superior to the control group(P < 0.05&P < 0.01). Follow up for 13-25 months (16.34 ± 4.25) after surgery showed no complications in the observation group, while there were two cases of nerve injury in the control group, with no statistically significant difference (P > 0.05). There were two cases of postoperative recurrence in the observation group with no symptoms and nine cases of recurrence in the control group with mild symptoms and did not require further treatment, which had statistical difference (P < 0.05).

CONCLUSIONS: Arthroscopic cystectomy and oper surgery both have definite clinical efficacy in treating popliteal cyst, which relying on prospective research to determine the optimal solution.

PMID:40227372 | DOI:10.1007/s00264-025-06527-y

Neck reconstruction in burn sequelae: A comparison of full-thickness skin grafts with traditional tie-over versus negative pressure wound therapy for both recipient site preparation and graft fixation

Injury -

Injury. 2025 Apr 12:112323. doi: 10.1016/j.injury.2025.112323. Online ahead of print.

ABSTRACT

BACKGROUND: Neck reconstruction for burn sequelae can be effectively achieved through release procedures and lower abdomen skin transplantation. This article describes cases in which full-thickness skin grafts (FTSGs) from the lower abdomen were used as donor areas. Although the benefits of negative pressure wound therapy (NPWT) for graft integration are known, its dual use for recipient site preparation and intraoperative graft fixation, specifically in the neck, has been scarcely described. This study evaluates both applications of NPWT-preoperative wound bed optimization and intraoperative graft fixation-highlighting their combined impact on graft take and patient outcomes.

METHODS: Patients treated at a referral burn center between March 2021 and October 2023 with severe neck contractures underwent scar release and FTSG transplantation. Two techniques for graft fixation were compared: the traditional tie-over method and NPWT. Graft integration rates, necrosis percentages, and postoperative complications were assessed.

RESULTS: The study included six patients (tie-over group: 2; NPWT group: 4). The NPWT group demonstrated clinically favorable graft integration rates (92.5 %) and lower necrosis rates (7.5 %) compared with the tie-over group (76.5 % and 23.5 %, respectively). The NPWT technique also resulted in shorter hospital stays and fewer complications.

CONCLUSIONS: The combined use of NPWT for recipient site preparation and intraoperative graft fixation clinically improves graft integration and reduces complications in neck burn reconstruction. These findings suggest that NPWT should be considered a standard of care in settings where resources allow.

PMID:40222842 | DOI:10.1016/j.injury.2025.112323

Based on the diamond concept, application of platelet-rich plasma in the treatment of aseptic femoral shaft nonunion: A retrospective controlled study on 66 patients

Injury -

Injury. 2025 Apr 1;56(6):112325. doi: 10.1016/j.injury.2025.112325. Online ahead of print.

ABSTRACT

BACKGROUND: Biologics, particularly platelet-rich plasma (PRP), have gained attention for promoting bone healing. This study assesses the efficacy of PRP-enhanced therapy in treating aseptic femoral shaft nonunion.

METHODS: This retrospective study analyzed patients who underwent femoral fracture nonunion revision surgery at a high-level trauma center between January 2021 and April 2024. Patients were divided into two groups: Group 1 (PRP-enhanced) and Group 2 (non-PRP). Group 1 received internal fixation with auxiliary plate reinforcement, PRP-enriched grafts, and bioactive center creation. The primary endpoint was bone healing rate and time to healing; secondary endpoints included lower limb function, pain scores, complications, and risk factors for nonunion at final follow-up.

RESULTS: Sixty-six patients were included (25 in Group 1, 41 in Group 2). At final follow-up, all patients in Group 1 healed, while 80.49 % of Group 2 healed (p = 0.049). The average healing time was shorter in Group 1 (7.61 months) compared to Group 2 (11.19 months) (p < 0.001). Group 1 had superior lower limb function and pain scores (p < 0.001). Long-term smoking (OR = 9.47, 95 % CI 1.39-64.51, P = 0.022) and inappropriate post-operative weight bearing (OR = 7.62, 95 % CI 1.12-51.57, P = 0.038) were identified as risk factors for nonunion.

CONCLUSION: In nonunion revision surgery, PRP-enhanced therapy significantly improves bone healing rates, reduces healing time, and carries fewer safety risks than traditional bone grafting. It offers an effective approach for nonunion treatment and provides a standardized clinical application for PRP in fracture nonunion surgeries.

PMID:40222318 | DOI:10.1016/j.injury.2025.112325

Repurposing of activating transcription factor 3 (ATF3) activator molecules with potential wound-healing effects

Injury -

Injury. 2025 Apr 4;56(6):112314. doi: 10.1016/j.injury.2025.112314. Online ahead of print.

ABSTRACT

BACKGROUND: Wound healing is a complex and regulated process that involves the coordinated action of key signaling pathways. Activating transcription factor 3 (ATF3) is a stress-inducible protein that has recently emerged as a critical modulator of cellular responses to injury, including those involved in wound healing.

AIM: The aim of this study was to explore the repurposing of existing pharmacological agents to activate ATF3 and evaluate their potential to enhance wound healing factors.

METHODS: We selected three compounds: retin-A, furosemide, and acrivastine based on their ability to modulate ATF3 expression and assessed their effects on wound healing processes in primary cell cultures. We evaluated wound healing-related genes such as LL-37, HBD-2, HBD-3, and VEGFA by qPCR, and a wound healing scratch assay using keratinocytes was conducted to evaluate cell migration.

RESULTS: Interestingly, retin-A induced the expression of key wound healing-related genes, including HBD-2, HBD-3, LL-37, and VEGF. Also, retin-A was the only compound showing wound healing effects, while furosemide and acrivastine did not exhibit any noticeable activity.

CONCLUSION: Our research highlights the potential of retin-A as therapeutic agents to improve wound healing, particularly in chronic wound models.

PMID:40220516 | DOI:10.1016/j.injury.2025.112314

Screw fixation of superior pubic ramus fractures using a modified technique with a pre-bent guidewire in curved transpubic corridors - A non-inferiority pilot study

Injury -

Injury. 2025 Apr 3;56(6):112318. doi: 10.1016/j.injury.2025.112318. Online ahead of print.

ABSTRACT

INTRODUCTION: Transpubic screw fixation is a valuable option for stabilization of superior pubic ramus fractures. However, insertion of a transpubic screw can be challenging or sometimes even impossible due to a narrow or curved transpubic screw corridor, which is present in 38 % of cases. To overcome this problem, a modified technique for insertion of a transpubic screw by advancing a pre-bent guidewire in an ESIN-like fashion is described.

MATERIALS AND METHODS: A retrospective, non-inferiority pilot study with patients, who received a transpubic screw, was performed to investigate potential procedure-associated complications as well as short-term radiological and clinical outcomes of the modified technique in comparison to the classical technique for insertion.

RESULTS: From 01/2021 to 04/2024, 24 transpubic screws were inserted at two major trauma centers, of which nine screws were inserted using the modified technique. Ten patients with a total of eleven transpubic screws (modified technique: 5; classical technique: 6) were available for this pilot study. One patient from the modified technique subgroup experienced a screw migration without affecting fracture healing and without necessitating hardware removal. The complication rate of the modified technique was not significantly inferior to the classical technique (p = 0.50). Residual displacement of the pubic ramus fracture was not significantly inferior using the modified technique compared to the classical technique (modified: 5.0 ± 2.2 mm; classical 4.4 ± 3.3 mm; p = 0.38). The clinical outcome was not significantly inferior using the modified technique compared to the classical technique regarding VAS pain (modified: 2.4 ± 4.3; classical 2.6 ± 2.5; p = 0.47), VAS satisfaction (modified: 8.8 ± 1.8; classical 9.0 ± 1.0; p = 0.42) and Majeed score (modified: 82.0 ± 12.6; classical 90.0 ± 12.5; p = 0.17).

CONCLUSION: The modified technique for insertion of a transpubic screw using a pre-bent guidewire is feasible in narrow and particularly curved transpubic corridors. It was not inferior compared to the classical technique regarding complications as well as short-term radiological and clinical outcomes.

PMID:40215699 | DOI:10.1016/j.injury.2025.112318

Long-term implant survival, functional, and radiological assessment of cemented stem in revision hip arthroplasty

International Orthopaedics -

Int Orthop. 2025 Apr 11. doi: 10.1007/s00264-025-06526-z. Online ahead of print.

ABSTRACT

PURPOSE: Revision total hip arthroplasty (rTHA) is an increasingly common procedure due to the growing number of primary total hip arthroplasties (THAs) performed worldwide. This study evaluates the long-term implant survival, functional outcomes, and radiographic performance of cemented femoral stem (Beznoska s.r.o., Kladno, Czechia) in rTHA.

METHODS: A retrospective analysis was conducted on 183 patients who underwent rTHA with cemented stem between March 2012 and December 2023. The mean follow-up duration was 71.26(± 39.31) months. Implant survival was analyzed using Kaplan-Meier survival estimates, and failure modes were assessed. Radiographic changes were classified using the Gruen Zones system. Functional outcomes were evaluated using the Harris Hip Score (HHS). Cox proportional hazard models were applied to identify prognostic factors influencing implant survival.

RESULTS: The five-year implant survival rate was 98.1%, declining to 83.9% at twelve years. The overall failure rate was 3.83%, with periprosthetic infection (4 cases) being the most common cause, followed by aseptic loosening (2 cases). Radiographic changes were observed in 24.03% of cases, predominantly in Gruen Zones 2, 6, and 1. Functional outcomes were favorable, with a mean HHS of 81.28(± 5.74), comparable to outcomes reported for uncemented revision stems. Age, stem diameter, and stem length did not significantly impact implant survival.

CONCLUSION: The cemented stem demonstrated favourable long-term survival, with high implant retention rates. Functional outcomes indicated overall satisfactory performance. Radiographic evaluation revealed localized changes around the implant, predominantly in Gruen Zones 2, 6, and 1. Implant failure was relatively rare, with periprosthetic infection being the most common cause.

PMID:40214745 | DOI:10.1007/s00264-025-06526-z

Fragment-specific fixation of simple and complex tibial plateau fractures using mini fragment plates

Injury -

Injury. 2025 Mar 27;56(6):112301. doi: 10.1016/j.injury.2025.112301. Online ahead of print.

ABSTRACT

BACKGROUND: In some multi-fragment tibial plateau fracture patterns, it may be more technically demanding to provide the appropriate support when using anatomic pre-contoured proximal tibial plates or other small fragment plates, especially when buttressing smaller apex-directed fracture fragments. The purpose of this study is to describe our surgical technique and highlight the potential role of low profile, mini fragment (2.0_2.7 mm) plates in the surgical management of different types of tibial plateau fractures.

METHODS: This is a retrospective study of 45 cases (45 patients, 31 males, mean age of 43.5 years) who had unicondylar or multicondylar tibial plateau fractures and were surgically managed using mini fragment plates, either as supplementary or standalone implants. The clinical notes and radiographs were reviewed to determine performance and complications, with particular focus on bony union, loss of reduction, implant failure, and soft tissue complications.

RESULTS: No intraoperative complications were recorded, and after a mean of 50.7 months, all the fractures have united. Two cases had knee stiffness and required manipulation under anesthesia, while only one case of secondary mild joint space depression was noted in the follow-up radiographs. No cases of nonunion, implant failure, or other cases of loss of reduction were recorded at the last radiolographic follow-up. Two patients required plate removal, at 4 months (a skeletally immature patient) and 18 months (another patient presented with secondary wound infection) postoperatively after fracture union. At the last radiographic follow-up, the average postoperative knee flexion was 121 degrees (range, 100-140), and the average postoperative Kellgren-Lawrence OA grade was 1 (range, 0-4).

CONCLUSIONS: The low-profile mini fragment plates are effective implants that may be safely used, either in association with other proximal tibial anatomic plates or as standalone implants, depending on the fracture configuration, with overall good outcomes.

PMID:40209613 | DOI:10.1016/j.injury.2025.112301

Nationwide analysis of pelvic and acetabular fracture surgeries in Japan: The impact of aging and healthcare resources

Injury -

Injury. 2025 Apr 2;56(6):112316. doi: 10.1016/j.injury.2025.112316. Online ahead of print.

ABSTRACT

PURPOSE: This study investigates Japanese trends in Open Reduction and Internal Fixation (ORIF) surgeries for acetabular and pelvic fractures, focusing on age, gender, regional disparities, and how orthopedic surgeon distribution affects surgical volumes, aiming to identify factors contributing to geographic variations.

METHODS: Surgical volumes for acetabular (K124-2) and pelvic (K125) fractures were categorized by age, gender, and prefecture in the National Database of Health Insurance Claims and Specific Health Checkups of Japan (2016-2022). Correlation analyses assessed relationships between surgical volumes, aging populations, and orthopedic surgeon availability.

RESULTS: Surgical volumes of the elderly increased among individuals over 65, with a notable rise in female pelvic fractures. Acetabular fractures were more prevalent in younger males. Urban areas with more orthopedic surgeons showed higher surgical volumes (p < 0.0001), while aging population rates correlated negatively (p < 0.0001).

CONCLUSION: ORIF for acetabular and pelvic fractures is increasing in Japan's aging population. Surgeon distribution influences surgical volumes, highlighting the need for treatment guidelines in primary care and telemedicine-based strategies.

PMID:40209612 | DOI:10.1016/j.injury.2025.112316

Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial

JBJS -

J Bone Joint Surg Am. 2025 Apr 10. doi: 10.2106/JBJS.24.01080. Online ahead of print.

ABSTRACT

BACKGROUND: Vitamin C shows strong anti-inflammatory and analgesic effects, so we explored whether it can replace glucocorticoids in reducing pain and inflammation after total hip arthroplasty (THA).

METHODS: In this prospective trial, a consecutive series of 107 patients (43.0% men, 56.8 ± 10.1 years of age, 100% Han Chinese) who underwent THA due to end-stage hip disease at our medical center between January 2023 and January 2024 were randomized to receive vitamin C, dexamethasone, or neither dexamethasone nor vitamin C after surgery. The 3 groups were compared in terms of the primary outcomes of pain reported on a visual analogue scale (VAS), perioperative morphine use, and blood indices of inflammation and fibrinolysis as well as in terms of secondary outcomes of efficacy and safety.

RESULTS: Compared with patients in the control group, those who received vitamin C or dexamethasone reported a significantly lower VAS pain score on postoperative day 1, had significantly lower perioperative morphine consumption, and demonstrated significantly lower blood levels of C-reactive protein on days 1 and 2. The 2 groups also showed a significantly lower rate of rescue analgesia on postoperative day 1 and significantly higher Harris hip scores of joint function at 2 and 12 weeks after surgery, as well as significantly smaller thigh circumference and a lower rate of swelling on the first 2 days after surgery. Either treatment was associated with a significantly lower rate of postoperative nausea and vomiting. Dexamethasone was associated with greater blood glucose levels after surgery.

CONCLUSIONS: Vitamin C may be an effective substitute for glucocorticoids for reducing morphine use and the risk of nausea or vomiting and for improving joint function after THA without side effects causing blood glucose fluctuations.

LEVEL OF EVIDENCE: Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.

PMID:40208930 | DOI:10.2106/JBJS.24.01080

Weekend open reduction and internal fixation of distal radius fractures associated with higher complication and readmission rates: a nationwide analysis of two hundred and sixty six thousand, three hundred and seventy eight patients

International Orthopaedics -

Int Orthop. 2025 Apr 10. doi: 10.1007/s00264-025-06517-0. Online ahead of print.

ABSTRACT

PURPOSE: The "weekend effect" suggests that patients operated upon weekends may experience worse outcomes. This study evaluates whether the day of the week impacts outcomes and costs of open reduction and internal fixation (ORIF) surgery for distal radius fractures (DRF) in a large nationwide cohort.

METHODS: A retrospective cohort study was conducted using data from the PearlDiver Mariner M165Ortho dataset, which covers a U.S. population of over 165 million from 2010 to 2022. Patients who underwent ORIF surgery for DRF were categorized into weekday and weekend groups. Demographics, comorbidities, and adverse outcomes within six months and two years post-surgery were analyzed.

RESULTS: Of the 266,378 patients who underwent ORIF for DRF with at least two years of follow-up, 252,866 had surgery on weekdays, while 13,512 had surgery on weekends. The weekend group exhibited higher rates of surgical site infection (SSI) (OR: 2.29[95%CI = 1.51-3.48], P < 0.001), hardware failure (OR: 5.80[95%CI = 1.13-31.25], P = 0.042), and readmissions (OR: 2.48[95%CI = 2.12-2.91], P < 0.001) at six months post-operatively. At two years post-operatively, the weekend group continued to show higher rates of complications including SSI (OR: 1.66[95%CI = 1.16-2.36], P = 0.005), malunion (OR: 1.44[95% CI = 1.06-1.93], P = 0.017), and readmission (OR: 1.55[95%CI = 1.39-1.74], P < 0.001). Mean total surgical costs were 16.4% higher in the weekend group ($2,394.85 vs. $2,057.88, P < 0.001).

CONCLUSIONS: This nationwide analysis demonstrates a significant "weekend effect" in ORIF surgery for DRF, with weekend surgeries associated with substantially higher complication rates, readmissions, and costs. These findings highlight the need for systemic changes to ensure consistent quality of care throughout the week, including improved weekend staffing, standardized protocols, and resource allocation.

LEVEL OF EVIDENCE: III (Retrospective cohort).

PMID:40208269 | DOI:10.1007/s00264-025-06517-0

Biomechanical comparison of different double plate constructs for distal supracondylar comminuted femur fractures (AO/OTA 33-A3)

Injury -

Injury. 2025 Apr 1;56(6):112324. doi: 10.1016/j.injury.2025.112324. Online ahead of print.

ABSTRACT

INTRODUCTION: Dual plating for distal femoral fractures, especially with a metaphyseal comminution, is biomechanically superior compared to single lateral plating, promotes fracture union and prevents complications. However, the optimal placement and length of the additional medial plate are still unknown. Thus, we aimed to biomechanically compare three different double plate constructs for distal femoral fractures.

MATERIALS AND METHODS: A distal femoral fracture with a metaphyseal comminution (AO/OTA 33-A3) was created in synthetic femora and stabilized according to the following groups of 6 specimens each: Single lateral plate (SP), double plate with anteromedial oblique locking plate (DPOB), double plate with parallel medial locking plate with 4 screws (DP4S) and double plate with parallel medial locking plate with 6 screws (DP6S). Afterwards, the femora were tested axially with a quasi-static load of 400 N as well as torsionally with 5 Nm of internal and external rotation. Interfragmentary motion and rotation were measured with an optical 3D motion analysis system.

RESULTS: Fracture gap motion and varus-valgus tilt under axial testing were significantly lower with DPOB, DP4S and DP6S than with SP (p = 0.02) without a significant difference between the double plate constructs. DP4S and DP6S showed a significant lower anteroposterior tilt under axial loading than SP (p = 0.02), whereas DPOB showed no significant difference compared to SP but had a significantly higher anteroposterior tilt than DP6S (p = 0.02). Under internal and external rotation testing, anteroposterior shift was significantly different, and axial rotation was significantly lower with DPOB, DP4S and DP6S compared to SP (p = 0.02) without a significant difference between the double plates.

CONCLUSION: Dual plating is biomechanically superior under axial and torsional loading compared to the traditional single lateral plating for distal femoral fractures with metaphyseal comminution. A parallel arrangement of double plates is biomechanically more effective in resisting anteroposterior tilt, whereas the length of parallel medial plates (with 4 or 6 screws) has no influence on the biomechanical performance.

PMID:40203770 | DOI:10.1016/j.injury.2025.112324

Description and prognostic factors of a cohort of polytraumatized patients with spinal injury in a level I trauma center

Injury -

Injury. 2025 Apr 1;56(6):112319. doi: 10.1016/j.injury.2025.112319. Online ahead of print.

ABSTRACT

INTRODUCTION: Traumatic spinal injuries are a significant public health issue due to their high frequency and severity, impacting the entire healthcare system, especially when neurological sequelae are involved. These injuries require comprehensive resuscitative management, prioritizing spinal injuries within the context of associated injuries. Understanding the epidemiology of spinal fractures in polytraumatized patients is essential for improving care planning, primary prevention methods, and hospital management.

METHODS: This retrospective, single-center, observational study used the TRAUMABASE database from 2018 to 2022 to provide an epidemiological overview of polytraumatized patients with spinal fractures treated in a level I trauma center. Patients admitted to the Post-Anesthesia Care Unit (PACU) with at least one spinal fracture were included, excluding those with isolated transverse process fractures or incomplete clinical files. Data collected included demographics, injury mechanism, Injury Severity Score (ISS), type of spinal lesion, Glasgow Coma Scale (GCS), surgical management, length of hospital stay, and mortality.

RESULTS: From 2018 to 2022, 561 patients with spinal fractures in the context of polytrauma were treated, with 386 patient records analyzed after exclusions. The mean age was 43 years, with a majority being male (75.1 %). The main injury mechanisms were falls from height (47.7 %) and traffic road accidents (46.4 %). Spinal surgery was performed on 53 % of patients, with a mean delay of 2.8 days from trauma to surgery. The overall mortality rate was 14.8 %, with neurological impairment, higher age, higher ISS score, lower GCS score, and absence of spinal surgery as unfavorable prognostic factors. The mean cost of hospitalization per patients was 76.854 ± 53.719 euros [3.502; 65.6623].

DISCUSSION: This study highlights the severity of polytraumatized patients with spinal lesions, with a mean ISS score of 24.4 and frequent associated severe traumatic brain injuries. The main injury mechanisms were falls from height and traffic road accidents, with a high representation of self-inflicted injuries. Overall, the study provides valuable insights into the management and outcomes of polytraumatized patients with spinal injuries.

PMID:40203769 | DOI:10.1016/j.injury.2025.112319

Outcomes of Lumbosacral Hemivertebra Resection and Short Segmental Fusion to Skeletal Maturity

JBJS -

J Bone Joint Surg Am. 2025 Apr 9. doi: 10.2106/JBJS.24.01181. Online ahead of print.

ABSTRACT

BACKGROUND: The present study aimed to assess the long-term outcomes of lumbosacral hemivertebra (LSHV) resection and short segmental fusion in a pediatric population and to assess the evolution of deformity curves.

METHODS: Patients who sought medical attention at our institution between 2010 and 2018 were assessed for eligibility. A classification of R10 and U9 or higher for the distal radius and ulna, respectively, was used to indicate maturity. Imaging parameters and quality-of-life scores were recorded at postoperative follow-up visits. Analyses were performed for the entire group and for subgroups of patients with and without a curve progression.

RESULTS: A total of 15 male and 15 female patients were included, with a mean age of 6.9 ± 2.4 years at the time of surgery. The main curve averaged 26.6° ± 6.5° preoperatively, 7.5° ± 4.6° (p < 0.001) at 3 months postoperatively, and 8.6° ± 3.2° (p = 0.205) at the latest follow-up. In the coronal plane, the coronal balance averaged 21.3 ± 16.7 mm preoperatively, 11.4 ± 8.5 mm (p = 0.007) at 3 months postoperatively, and 11.2 ± 8.9 mm (p = 0.858) at the latest follow-up. A total of 7 complications were recorded in 6 patients (20.0%). The Scoliosis Research Society 22-Item Questionnaire (SRS-22) total score (p < 0.001), appearance score (p < 0.001), and satisfaction score (p < 0.001) were all significantly different from preoperatively to postoperatively. Compared with the compensatory curve progression group, the non-progression group had a higher SRS total score (p = 0.013) and satisfaction (p < 0.001).

CONCLUSIONS: For pediatric patients <10 years old, LSHV resection and short segmental fusion could provide correction and global spine balance improvement. However, the observed loss of correction in the compensatory curve in some patients during the follow-up may compromise the satisfaction.

LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.

PMID:40203129 | DOI:10.2106/JBJS.24.01181

Open Reduction of Hip Dislocation Is Associated with Higher Rates of Proximal Femoral Growth Disturbance in Patients with Arthrogryposis Multiplex Congenita Than Idiopathic DDH: A Dual-Center Retrospective Cohort Study

JBJS -

J Bone Joint Surg Am. 2025 Apr 9. doi: 10.2106/JBJS.24.01119. Online ahead of print.

ABSTRACT

BACKGROUND: The sequelae of open reduction of developmental and/or syndromic hip dislocations include osteonecrosis/proximal femoral growth disturbance and residual dysplasia. There is limited information comparing the rates of these sequelae in patients with developmental dysplasia of the hip (DDH) and arthrogryposis multiplex congenita (AMC). We performed a dual-center retrospective cohort study to compare rates of proximal femoral growth disturbance and residual dysplasia between patients with DDH and AMC who had undergone open hip reduction for the treatment of non-traumatic hip dislocations.

METHODS: We identified patients <18 years of age who had undergone open reduction for the treatment of hip dislocation between 1981 and 2020 at 2 tertiary pediatric hospitals. Patients with AMC were matched by age against patients with DDH in a 1:2 ratio. Preoperative data included demographic characteristics, the severity of dislocation according to the International Hip Dysplasia Institute (IHDI) classification system, and the acetabular index. Outcomes included the acetabular index at 2 years postoperatively, the IHDI classification at the time of final follow-up, and the presence and grade of proximal femoral growth disturbance according to the Salter criteria at 2 years postoperatively and according to the Kalamchi and MacEwen (KM) classification system at the time of final follow-up.

RESULTS: Eighty-two patients (98 hips) with DDH were matched against 39 patients (49 hips) with AMC. The mean follow-up was 107 months (range, 24 to 443 months). There was no difference in the mean age at surgery (1.5 ± 0.7 versus 1.4 ± 1.3 years; p = 0.86), preoperative IHDI classification, acetabular index, or spica cast duration (p > 0.05 for all), but the DDH cohort had more females (83% versus 56%; p = 0.003). Postoperatively, the prevalence of proximal femoral growth disturbance was higher in the AMC group than in the DDH group according to the Salter criteria at 2 years (57% versus 21%; p < 0.001) and according to the KM criteria at the time of final follow-up (59% versus 16%; p < 0.001). At 2 years postoperatively, there was no difference between the DDH and AMC groups in terms of the acetabular index (31° ± 6.2° versus 29° ± 6.9°; p = 0.3) or reoperation rate (24% versus 20%; p = 0.68), but the AMC cohort had more IHDI grade II-IV hips than the DDH cohort (24% versus 9%; p = 0.02), reflecting re-subluxation/dislocation.

CONCLUSIONS: Open reduction for hip dislocation in patients with AMC was associated with a significantly higher rate of proximal femoral growth disturbance and re-subluxation/dislocation compared with that in patients with DDH, despite similar preoperative characteristics. This information may guide perioperative counseling for families of patients with AMC.

LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

PMID:40203125 | DOI:10.2106/JBJS.24.01119

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