Exploration of the relationship between the height of the popliteal artery injury plane and the risk of amputation
Injury. 2025 Mar 8;56(4):112233. doi: 10.1016/j.injury.2025.112233. Online ahead of print.
ABSTRACT
PURPOSE: The aim of the present study was to explore the impact of different planes of popliteal artery injury (PAI) on the risk of amputation in affected limbs.
METHODS: A retrospective analysis was conducted on ninety-four patients who underwent PAI; these patients were divided into an amputation group (n = 26) and a nonamputation group (n = 68) on the basis of whether limb preservation was successful. The data were reconstructed from computed tomography angiography (CTA) of the patients' lower limbs and measured via AW Volume Share 5 software. The height of the popliteal artery injury surface was quantified as follows: "L" was defined as the distance from the origin of the descending genicular artery of the contralateral limb to the origin of the anterior tibial artery; "S" was defined as the distance from the origin of the descending genicular artery of the affected limb to the blood flow interruption site; and "R" was defined as the ratio of S to L (S/L). The risk factors for amputation in patients with PAI were also analysed.
RESULTS: Univariate and multivariate logistic regression analyses revealed that R (odds ratio [OR]=0.876, P = 0.006,95 % CI:0.797-0.963), S (OR=0.792, P = 0.166,95 % CI:0.570-1.102), ischemic time (OR=1.195, P = 0.017,95 % CI:1.032-1.383), and compartment syndrome (OR=5.509, P = 0.055,95 % CI:0.967-31.376) were independent risk factors for amputation in patients with PAI. The receiver operating characteristic (ROC) curve revealed that the AUC values were 0.887 (P < 0.000, 95 % CI: 0.805-0.943) and 0.775 (P < 0.000, 95 % CI: 0.677-0.854) for R and S, respectively. The diagnostic efficiency was highest when the diagnostic threshold values were 0.573 and 11.3 cm, for R and S, respectively. Moreover, the AUCR was greater than the AUCS (Z = 2.403, P = 0.0162).
CONCLUSION: The height of the PAI plane is an independent risk factor for amputation in patients with PAI. Greater planes of vascular injury result in greater risk of amputation. R is better than S in the diagnosis of amputation risk in patients with PAI.
PMID:40073711 | DOI:10.1016/j.injury.2025.112233