International Orthopaedics

State-of-the-art review: The advantage and use of Wide Awake Local Anaesthesia No Tourniquet (WALANT) for nerve decompression surgery

Int Orthop. 2025 Feb 14. doi: 10.1007/s00264-025-06432-4. Online ahead of print.

ABSTRACT

PURPOSE: Wide Awake Local Anesthesia No Tourniquet (WALANT) has gained significant attention since its introduction in 2005. Over 343 publications since 2013 highlight its increasing use in nerve decompression surgeries. WALANT is known for its safety benefits, cost-effectivenes and improved patient experience compared to traditional sedation and tourniquet-based methods. This review examines the advantages of WALANT in nerve decompression surgery, emphasizing its growing adoption and benefits.

METHODS: A comprehensive review of the WALANT technique is provided, focusing on injection strategies, including buffered lidocaine with epinephrine, proper needle placement and generous volume of tumescent anesthesia. Specific injection protocols and surgical approaches are discussed for various nerve decompression procedures such as carpal tunnel, lacertus, cubital tunnel, radial tunnel and lateral intermuscular septum releases.

RESULTS: WALANT eliminates sedation-related risks such as nausea, aspiration pneumonia and thromboembolism, making it suitable for high-risk patients (ASA 4). It reduces healthcare costs by decreasing the need for post-anesthesia care units and operating in minor procedure rooms. The technique fosters greater surgeon-patient interaction, reduces hospital stays and avoids preoperative fasting and testing. WALANT has demonstrated positive outcomes across multiple nerve decompression procedures.

CONCLUSION: WALANT provides a transformative approach in nerve decompression surgery, offering enhanced safety, cost-effectiveness and improved patient-centered care. It significantly contributes to positive surgical outcomes, making it a valuable technique for both patients and healthcare providers.

PMID:39951053 | DOI:10.1007/s00264-025-06432-4

Long-term implant survival after debridement, antibiotics and implant Retention (DAIR) for acute prosthetic joint infections: is it a viable option beyond four weeks after index arthroplasty?

Int Orthop. 2025 Feb 14. doi: 10.1007/s00264-025-06422-6. Online ahead of print.

ABSTRACT

PURPOSE: Debridement, Antibiotic Treatment, and Implant Retention (DAIR) is considered the first-line treatment for early acute Prosthetic Joint Infection (PJI). This study aims to evaluate the five year success rates of early acute PJI managed with DAIR taking into consideration the time from the index surgery.

MATERIALS AND METHODS: A retrospective analysis of medical charts for 291 consecutive patients with acute PJI occurring within the first three months after primary or revision arthroplasty was conducted. Patients were stratified into two groups based on DAIR timing: Group (A) patients who underwent DAIR within the first four weeks post-arthroplasty; Group (B) patients who underwent DAIR between five and 12 weeks post- arthroplasty. Success rate was defined as implant in place, without signs of infection and not under suppressive antibiotic treatment.

RESULTS: The overall five year success rate for the entire cohort at five years was 62.2%. The mortality rate during the study period was 8.2%. The five year success rate was 64.4% (141 of 219) for Group A and 55.6% (40 of 72) for Group B (p = 0.21). Including deceased patients without signs of infection and retained implants as successful cases, the five year success rates increased to 69.9% for Group A (153 out of 219) and 69.4% for Group B (50 out of 72). The implant survival rate at five years was 73% for Group A and 71% for Group B.

CONCLUSION: Our findings indicate that there are no significant differences between patients who undergo a DAIR procedure within four weeks from those performed between week five and 12. Importantly, the overall success rate decreased from 75.6 to 62.2% in the last three years of follow-up.

PMID:39951052 | DOI:10.1007/s00264-025-06422-6

Chronic elbow dislocations: shorterm results of the "French elbow connection" technique

Int Orthop. 2025 Feb 13. doi: 10.1007/s00264-025-06447-x. Online ahead of print.

ABSTRACT

PURPOSE: The aim of the present study was to describe our experience with French Elbow Connection (FEC) (i.e. elbow reduction and triple ligamentoplasty) for patients with chronic elbow dislocation (CED).

MATERIALS AND METHODS: We performed a retrospective review of 12 patients in two departments of orthopaedic surgery undergoing the FEC procedure for CED between 2019 and 2024. The median follow-up was 1.80 years (IQR 1.00; 1.97). Range of motion, mean Mayo Elbow Performance score (MEPS), visual analog scale (VAS), elbow stability, and radiographic outcome were recorded.

RESULTS: Median MEPS and VAS were 90.00 points (IQR 75.60; 100.00) and 0 (IQR 0; 1.50), respectively. Eight (66%) patients reported no pain. The median active flexion-extension and prono-supination arcs were 145°(IQR 102.60; 150.00), and 170°(IQR 155.03; 170.00) respectively. Persistent valgus or varus instability was identified in 2 (17%), and 1 (8%) patient respectively. Size patients (50%) were diagnosed with osteoarthritis (OA) and 1 patient experienced worsening postop OA (from grade 1(preop) to 3(postop)).

CONCLUSION: CED is a complex condition that presents elbow surgeons with unique challenges. The FEC procedure allows for immediate active ROM and yielded satisfactory short-term outcomes in our hands. Larger, longer-term studies will be necessary to assess reproducibility and confirm results can be maintained over time.

LEVEL OF EVIDENCE: level IV; therapeutic study (case series [no, or historical, control group]).

PMID:39945805 | DOI:10.1007/s00264-025-06447-x

S-design osteotomy and internal fixation for multiplanar and acute correction of deformity in infantile Blount's disease - preliminary results from single centre series

Int Orthop. 2025 Feb 13. doi: 10.1007/s00264-025-06427-1. Online ahead of print.

ABSTRACT

PURPOSE: This is a preliminary study with short-term follow up to determine the safety and efficacy of the S-design osteotomy and internal fixation for acute varus and rotational correction technique in infantile Blount's disease.

METHODS: We performed a retrospective series in our institutional hospital. An S-design osteotomy for multiplanar, acute correction followed by internal fixation was performed for Blount's disease patients. Effectiveness was measured by comparing pre-and post-operative tibiofemoral angle (TFA) and metaphyseal-diaphyseal angle (MDA). Safety was determined by the number of neurological deficits and compartment syndromes occurred post operatively. Functional outcome was assessed using the Lower Extremity Functional Scale (LEFS). All patients underwent a one-year follow-up after surgery.

RESULTS: Nineteen patients (total of 31 extremities) were included in this study and classified into TFA less than 40 degree (group A) and more than 40 degree (group B). No neurological deficits nor compartment syndrome occured in either group. Regardless the severity of pre-operative deformity, both groups achieved significant corrections. Post operatively there was no significant difference in TFA in Group A and Group B (1.70 and 3.00 respectively, with p value of 0.147) and MDA (4,60 and 6,0 respectively, with p value of 0.327). This indicated there was no correlation between preoperative deformity and postoperative results. LEFS score of group A (73.85 ± 2.73) and Group B (73.85 ± 2.73) showed equally good results in both groups (p = 0.293).

CONCLUSION: This preliminary study with short-term follow up suggested that the S-design osteotomy effectively corrected internal rotation and varus while aiding limb length. The correction of internal rotation is accomodated by performing box osteotomy between the two horizontal (proximal and distal) lines of osteotomy, with safe and effective results. Acute correction is a safe and effective strategy for severe Blount's disease. Longer-term follow-up is awaited.

LEVEL OF EVIDENCE: V.

PMID:39945804 | DOI:10.1007/s00264-025-06427-1

Long-term outcomes of small head metal-on-metal compared to ceramic-on-polyethylene primary total hip arthroplasty: a registry-based cohort study

Int Orthop. 2025 Feb 12. doi: 10.1007/s00264-025-06437-z. Online ahead of print.

ABSTRACT

PURPOSE: We aimed to compare the long-term outcomes of small-head (28 mm) metal-on-metal (MoM) total hip arthroplasty (THA) to ceramic-on-polyethylene (CoP) THA using the same cup.

METHODS: All primary elective MoM and CoP THAs performed 1998-2011 were prospectively included in a local registry. Patients were followed until 31 December 2022. Outcomes were all-cause revision, complications and mortality. The uncemented Morscher 28 mm monobloc press-fit cup was used in all THAs.

RESULTS: Overall, 3257 THAs were included, 864 MoM (mean age 63) and 2393 CoP THAs (mean age 72). Mean follow-up of the cohort was 12.9 years (maximum 26.8 years). Revision for any cause was performed in 85 MoM and 79 CoP THAs. Cumulative incidence of all-cause revision at 20 years was 13.2% (95% CI 10.6 to 16.3) in MoM and 6.3% (95% CI 4.8 to 8.3) in CoP group. Adjusted hazard ratio for all-cause revision was 1.88 (95% CI 1.34 to 2.65) comparing MoM vs. CoP. Diagnoses at revision were mainly aseptic loosening (33%) and adverse local tissue reactions (33%) in MoM and aseptic loosening in CoP group (44%). The smoothed hazard function revealed the largest difference in instantaneous revision rate between three and 14 years postoperative. After that period no difference was observed.

CONCLUSION: Overall, the cumulative risk of all-cause revision was almost twice as high in patients with a small head MoM as compared to a CoP THA over the 20-year period. However, most of the excess in revisions among MoM patients occurred between three and 14 years postoperative.

PMID:39937240 | DOI:10.1007/s00264-025-06437-z

Long-term comparative study evaluating the screw-cement construct for tibial defects in total knee arthroplasty: our experience

Int Orthop. 2025 Feb 12. doi: 10.1007/s00264-025-06439-x. Online ahead of print.

ABSTRACT

PURPOSE: Total knee arthroplasty (TKA) is the preferred treatment for end-stage knee osteoarthritis, but challenges arise with severe angular deformities and associated tibial bone loss. The cement screw construct has emerged as a promising technique for managing these defects, offering advantages such as cost-effectiveness, accessibility, and ease of implementation. This research evaluated the clinical, functional and radiological outcome of screw-cement construct for the tibial defects in TKA.

METHOD: This retrospective study aimed to evaluate the long-term functional outcomes and success rate of the cement screw construct in patients with significant tibial defects. Sixty-five patients (104 knees) undergoing TKA were divided into two groups: conventional TKA (Group A) and TKA with screw-cement construct (Group B). Demographic, clinical, and radiological data were collected, with a follow-up duration of at least eight years.

RESULTS: The study revealed comparable demographic characteristics between groups. Both cohorts exhibited significant postoperative improvements in knee morphology and clinical outcomes. Group B demonstrated a higher incidence of radiolucency around the tibial tray, although no progressive complications were observed. Implant survival rates were similar between groups, with complications such as aseptic loosening and infections occurring in both without significant difference.

CONCLUSIONS: This study emphasised the viability of the screw-cement construct for managing uncontained tibial defects during TKA, providing evidence of its efficacy, and cost-effectiveness and suggesting its potential as a standard approach for tibial defects till 20 mm.

PMID:39937239 | DOI:10.1007/s00264-025-06439-x

Pharmaceutical considerations in treating neuropathic pain in athletes

Int Orthop. 2025 Feb 12. doi: 10.1007/s00264-025-06440-4. Online ahead of print.

ABSTRACT

Neuropathic pain is a complex and challenging condition that arises from abnormal processing of somatosensory information, often following nerve injury or dysfunction. Its diagnosis involves a detailed clinical history, sensory examination, and diagnostic tests such as electromyography, nerve conduction studies, and MRI to identify nerve damage or structural causes. In athletes, neuropathic pain can result from nerve entrapment syndromes, post-surgical complications, or peripheral nerve injuries, with unique challenges in pain assessment due to psychological factors and exercise-induced changes. Pharmacological management primarily includes anticonvulsants (e.g., gabapentin, pregabalin) and antidepressants (e.g., tricyclics, SNRIs), tailored to minimize side effects that could impair athletic performance. Effective treatment requires a careful balance to manage pain while maintaining physical capabilities. When treating athletes for neuropathic pain, healthcare providers must ensure prescribed medications comply with World Anti-Doping Agency (WADA) regulations. Narcotics (opioids) and cannabinoids are prohibited in-competition. Glucocorticoids are also banned in-competition if administered via injection, orally, or rectally, and elevated levels in urine may lead to sanctions.

PMID:39937238 | DOI:10.1007/s00264-025-06440-4

Is synovectomy still of benefit today in total knee arthroplasty with rheumatoid arthritis?

Int Orthop. 2025 Feb 11. doi: 10.1007/s00264-025-06441-3. Online ahead of print.

ABSTRACT

PURPOSE: There is a lack of long-term data evaluating the impact of synovectomy versus no synovectomy during total knee arthroplasty (TKA) in patients with rheumatoid arthritis (RA). This study aimed to assess and compare bilateral TKA outcomes with and without synovectomy in the same patients over a similar follow-up period.

METHODS: A retrospective review was conducted on 65 bilateral staged posterior-stabilized (PS) fixed-bearing TKAs (28 men, 37 women) performed by a single surgeon on RA-affected knees, with an average follow-up of 17 years (range: 15-24 years). In the first knee, synovectomy was performed during TKA, while no synovectomy for the contralateral TKA. Outcomes assessed included Knee Society scores for knee and function, radiographic findings, complications, and patellar position using the Insall-Salvati ratio.

RESULTS: The synovectomy group had a higher rate of blood transfusion (23.3% vs. 16.6%; P < 0.01) and longer hospital stays (mean 9.60 days [95% CI: 6.56-13.63] vs. 6.51 days [95% CI: 5.50-9.52]; P < 0.001). The group without synovectomy demonstrated significantly better Knee Society Scores (89.1 vs. 80.2 points; P = 0.02) and greater range of motion (ROM) for flexion (130° vs. 102°; P = 0.01). Both groups had similar knee alignment, stability, and femoral and tibial component alignment. Patella baja was observed in six patients in the synovectomy group. Severe haematoma (n = 6) and deep infections (n = 4) were noted exclusively in the synovectomy group. Kaplan-Meier survivorship at 15 years was 81% (95% CI: 78-95) for TKA with synovectomy and 95% (95% CI: 90-100) for TKA without synovectomy.

CONCLUSION: Knees undergoing synovectomy during primary TKA exhibited reduced knee flexion, inferior Knee Society pain scores, and higher complication rates compared to contralateral knees without synovectomy. Omitting synovectomy in RA patients did not increase the risk of implant loosening.

PMID:39932578 | DOI:10.1007/s00264-025-06441-3

Imaging on the painful and compressed nerve: upper extremity

Int Orthop. 2025 Feb 10. doi: 10.1007/s00264-025-06436-0. Online ahead of print.

ABSTRACT

Compressive neuropathies of the upper extremity are a common cause of pain, weakness, and functional impairment, often resulting from chronic mechanical compression or entrapment of peripheral nerves in anatomical regions such as osteofibrous tunnels, fibrous bands, or muscular pathways. While traditional diagnostic methods, including clinical evaluation and electrophysiological studies, are essential, they are limited in localizing lesions and identifying underlying causes. Advances in ultrasonography (US) and magnetic resonance imaging (MRI), particularly MR neurography and high-resolution 3D volumetric imaging, have significantly improved the evaluation of peripheral nerves by enabling detailed visualization of nerve anatomy, adjacent structures, and muscle denervation patterns. This article reviews the role of these imaging techniques in diagnosing and managing compressive neuropathies affecting the brachial plexus, suprascapular, axillary, median, ulnar, and radial nerves, highlighting key imaging findings such as nerve thickening, signal abnormalities, and muscle changes. The integration of advanced imaging modalities into clinical practice enhances diagnostic accuracy, facilitates surgical planning, and improves treatment outcomes for patients with peripheral nerve compression.

PMID:39928139 | DOI:10.1007/s00264-025-06436-0

Immersive virtual reality in the rehabilitation of athlete nerve entrapments

Int Orthop. 2025 Feb 10. doi: 10.1007/s00264-025-06433-3. Online ahead of print.

ABSTRACT

INTRODUCTION: The implementation of Virtual Reality technology is approaching a breakthrough within the medical, and rehabilitation fields. The level of immersion in the virtual environment is profound and the potential applications are vast.

METHODS: This article reviews the capabilities of Virtual Reality in conjunction with the rehabilitation of nerve entrapments in sport athletes and examines the interactions between our body and brain within the virtual realm. In clinical practice it could be used as a complement to face-to-face therapy to asynchronous use by the patient in any location as a telerehabilitation system.

CONCLUSION: The use of Virtual Reality is a novel, potential, and promising tool in the treatment of nerve entrapments, even possible in the form of telerehabilitation. The response of body and brain in a virtual setting is good, the evolutions in technology can only improve this and this need to be substantiated by further scientific research.

PMID:39928138 | DOI:10.1007/s00264-025-06433-3

Three dimensionalprinted titanium block to reconstruct severe acetabular bone defects in primary hip arthroplasty

Int Orthop. 2025 Feb 8. doi: 10.1007/s00264-025-06444-0. Online ahead of print.

ABSTRACT

PURPOSE: Total hip arthroplasty (THA) with severe acetabular bone defect remains a challenge in clinic. The purpose of this study is to investigate the treatment technique by using the three-dimensional (3D) printing technology, and analyze the feasibility and preliminary effect of 3D printed personalized titanium blocks for acetabular defect reconstruction in primary THA.

METHODS: The clinical data of 35 patients with Paprosky type 3 acetabular defect, who underwent initial THA with 3D-printed titanium implants in our hospital from January 2017 to December 2019, were retrospectively analyzed. Among them, 21 cases were Paprosky type 3 A bone defects and 14 cases were Paprosky type 3B bone defects. The Harris Hip Score (HHS) was used to evaluate clinical outcomes, while imaging results were analyzed by hip rotation centres (V-COR and H-COR). In addition, postoperative complications were recorded.

RESULTS: The mean follow-up was 79.4 months (ranging from 63 to 94 months) and no patient was lost to follow-up. The total in-hospital blood loss of all patients was 462.9 ± 227.8 mL, accompanied with a blood transfusion rate of 31.4%. HHS improved from 44.5 ± 10.0 preoperatively to 85.1 ± 7.4 at the last follow-up (p < 0.001). Postoperative X-rays exhibited a good match between the 3D-printed titanium block and the acetabulum. V-COR decreased from 50.1 ± 4.7 mm preoperatively to 19.7 ± 1.8 mm postoperatively (p < 0.001). Similarly, H-COR improved from 33.1 ± 11.8 mm preoperatively to 29.7 ± 1.7 mm postoperatively (p > 0.05). Additionally, there were no significant changes in V-COR and H-COR at the last follow-up (p > 0.05). During follow-up, three cases of complications were observed, including two cases of wound redness and one case of partial sciatic nerve paralysis.

CONCLUSIONS: The 3D-printed personalized titanium block revealed accurate reconstruction, satisfactory radiographic and clinical outcomes, and low complication rates. This technique provides a reliable treatment strategy for primary THA in patients with severe acetabular bone defect.

PMID:39921749 | DOI:10.1007/s00264-025-06444-0

Sleep disturbances in elderly patients with distal radius fractures: a prospective observational study

Int Orthop. 2025 Feb 8. doi: 10.1007/s00264-025-06431-5. Online ahead of print.

ABSTRACT

PURPOSE: No previous studies have reported the presence of sleep disturbances or their association with baseline factors in elderly patients with distal radius fracture (DRF). This study aimed to describe the proportion of patients with sleep disturbances and analyze their association with baseline factors in patients older than 60 years with conservatively treated DRFs.

METHODS: This prospective observational study included 220 patients with extra-articular DRFs who completed the Pittsburgh Sleep Quality Index at two time points: two weeks after cast removal and at the one year follow-up. Sociodemographic, anthropometric, clinical, radiological, and patient-reported outcome measures were analyzed as baseline predictors, with measurements performed two weeks after cast removal.

RESULTS: At two weeks after cast removal, 166 (75.5%) patients had sleep disturbances. Sleep disturbances were associated with the affected dominant hand (β = 1.6; p = 0.04), high-energy injury (β = 3.8; p < 0.001), extra-articular comminuted metaphyseal DRFs (β = 2.3; p < 0.001), higher Tampa Scale of Kinesiophobia scores (β = 2.4; p < 0.001), higher Pain Catastrophizing Scale scores (β = 2.4; p < 0.001), higher Pain Anxiety Symptoms Scale-20 scores (β = 2.1; p < 0.001), and higher visual analogue scale scores (β = 4.1; p < 0.001). At the one year follow-up, 85 (38.6%) patients had sleep disturbances, which were associated with higher Tampa Scale of Kinesiophobia scores (β = 2.6; p < 0.001), higher Pain Catastrophizing Scale scores (β = 2.5; p < 0.001), and higher Pain Anxiety Symptoms Scale-20 scores (β = 1.8; p = 0.02).

CONCLUSIONS: A high proportion of elderly patients with DRF experienced sleep disturbances. Expanding our understanding of the interplay between sleep disturbances and baseline risk factors may lead to improved care and clinical outcomes for these patients. Future studies should incorporate the clinical management of sleep disturbances in patients with DRFs.

PMID:39921748 | DOI:10.1007/s00264-025-06431-5

Are high cutibacterium bacterial loads at the time of revision shoulder arthroplasty associated with more severe clinical signs or symptoms or increased risk of recurrent periprosthetic joint infection?

Int Orthop. 2025 Feb 8. doi: 10.1007/s00264-025-06442-2. Online ahead of print.

ABSTRACT

PURPOSE: Cutibacterium is commonly isolated from deep tissue samples taken at the time of revision shoulder arthroplasty, but the significance of these positive cultures is debated, and the impact of increasing bacterial loads on clinical outcomes is unclear. The objectives of this study were to (1) identify factors independently associated with high bacterial loads, and (2) compare patient-reported outcomes (PROs) and revision rates in patients found to have high Cutibacterium loads.

MATERIALS AND METHODS: Male patients undergoing single stage exchange with a minimum 2-year follow-up were included. Culture data were semi-quantitatively scored with the total Cutibacterium score (TShCuS). Two groups were compared: patients with a High Cutibacterium Load (HCL) group and those with Low Cutibacterium Load (LCL) group. PROs and revision rates were compared, and a multivariable analysis was conducted.

RESULTS: Of 68 male patients that underwent revision shoulder arthroplasty, 29 (42.6%) met the inclusion criteria for the HCL group, while 27 patients (39.7%) were in the LCL group. Mean follow-up was 4.7 ± 3 years. Patients with intraoperative humeral loosening had an 18.4 times increased risk of having high Cutibacterium loads (95% CI 2.1-154.4, p < 0.001). There were no significant differences in PROs or re-revision rates between the HCL and LCL groups.

CONCLUSIONS: Intraoperative humeral loosening was independently associated with high Cutibacterium loads found at the time of revision shoulder arthroplasty. Male patients with high bacterial loads treated with complete single stage exchange and antibiotics had patient-reported outcomes similar to those of patients with minimal to no load.

LEVEL OF EVIDENCE: III.

PMID:39921747 | DOI:10.1007/s00264-025-06442-2

Inter-hospital variation in early major complication rates following total hip arthroplasty: a population-based study

Int Orthop. 2025 Feb 7. doi: 10.1007/s00264-025-06423-5. Online ahead of print.

ABSTRACT

PURPOSE: Early major complications following total hip replacement (THR) occur rarely, but given the high volumes of THR, represent a major burden to patients and the system. The purpose of this study was to determine the influence of hospital-level surgical practices on early major complications across Ontario.

METHODS: We conducted a population-based retrospective cohort study of all adults in Ontario, Canada who underwent primary THR for osteoarthritis between January 1, 2009 and December 31, 2019. The primary outcome was early major surgical complications (composite of deep infection, periprosthetic fracture, dislocation, or revision surgery occurring within 1 year of surgery). Medical complications (thromboembolism, myocardial infarction, pneumonia) occurring within 30 days of surgery also were assessed. THR performed at centres with very low volumes were excluded a priori. Two-level hierarchical logistic regression models adjusted for age, sex and Charlson co-morbidity score were used to calculate each hospital's unique adjusted complication rate and 95% confidence interval.

RESULTS: During the study period, 95,912 patients (mean [SD] age 67 [11.0] years; 51,216 (53.4%) women) underwent THA at 56 hospitals across Ontario. Overall, 1,656 (1.7%) patients had a major surgical complication within 1 year. Major surgical complication rates varied seven fold between hospitals from 0.6 to 4.1%. After adjustment, 4 of 56 hospitals were low outliers (adjusted complication rate significantly below average) and 5 of 56 were high outliers (adjusted complication rate significantly above average). There were no hospital outliers for medical complications.

CONCLUSIONS: There was significant variation in early major surgical complication rates between Ontario hospitals that persisted after adjustment for patient age, sex and medical comorbidity. Feeding back adjusted outcomes in benchmarking reports may enable individual hospitals and surgeons better consider their own performance and scale up best practices from low outlier hospitals, which can play a role in educating other centres in their region.

PMID:39918565 | DOI:10.1007/s00264-025-06423-5

Risk factors for the development of premature physeal closure after a McFarland fracture in children

Int Orthop. 2025 Feb 5. doi: 10.1007/s00264-025-06428-0. Online ahead of print.

ABSTRACT

PURPOSE: In 1931, McFarland reported on medial malleolar physeal fractures and resulting deformities, which were later classified as Salter-Harris Type III and IV fractures of the medial malleolus. Ongoing controversy surrounding the factors that increase the risk for PPC in children with McFarland (MF) fracture.The retrospective study aimed to investigate the radiological and clinical outcomes of children treated surgically for MF fracture and evaluate the potential factors that increase the risk for premature physeal closure (PPC).

METHODS: We retrospectively reviewed 48 children who were surgically treated for MF fracture. Demographic data, including age at injury, gender, mechanism of injury, laterality, initial displacement, fracture type, time from injury to surgery, method of reduction, fixation method, time of hardware removal, and whether or not the patient developed PPC, were retrieved from the charts.

RESULTS: PPC occurred in 35.4% (17/48) of the patients. Our analysis revealed that patients with PPC were significantly younger than those without PPC (P < 0.001). Furthermore, our analysis revealed age and initial displacement as independent factors that increased the risk for PPC. Notably, age less than 11.5 years and initial displacement of more than 4.5 mm represented the cut-off points for an increased incidence of PPC. Overall, 11 out of 48 patients had limited ankle range of motion (ROM); mean ankle ROM in patients with PPC was lower than those without PPC (P = 0.006). Lower limb discrepancy was 2.5 cm in children, although three patients with PPC had a lower limb discrepancy measuring more than 2 cm, and five patients with PPC complained of postoperative pain.

CONCLUSIONS: Age and initial displacement are independent factors that increase the risk for PPC in children with MF fracture. Specifically, children aged under 11.5 years and those with initial displacement exceeding 4.5 mm are at a higher risk for PPC.

LEVEL OF EVIDENCE: Observational study.

PMID:39907773 | DOI:10.1007/s00264-025-06428-0

Beta-tricalcium phosphate combined with native bone proteins (β-TCP - NBP): a novel bone graft substitute for ankle and hindfoot arthrodesis

Int Orthop. 2025 Feb 4. doi: 10.1007/s00264-025-06429-z. Online ahead of print.

ABSTRACT

PURPOSE: The purpose of this prospective, multi-centre study was to assess the performance and safety of a combination of osteoconductive β-tricalcium phosphate and osteoinductive native bone proteins (β-TCP - NBP) used as alternative for autograft in ankle and hindfoot arthrodesis.

METHODS: Thirty-four patients enrolled underwent ankle or hindfoot arthrodesis with β-TCP - NBP and were evaluated radiographically, clinically, and functionally up to fifty-two weeks. The primary performance endpoint was fusion rate evaluated with CT at six months. Safety was assessed based on the severity and incidence of adverse events. Functional evaluation was performed using the American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hindfoot score and pain was recorded using the Visual Analogue Scale (VAS).

RESULTS: CT at 6 months showed that 85.3% had osseous bridging of the joint of ≥ 25%, 52.9% ≥50%, 8.8% <25% and 5.9% showed no bridging. The AOFAS score increased significantly from 60.4 ± 17.6 points at operation to 68.6 ± 17.2 points at six months and to 73.5 ± 17.7 points at 12 months. The group with fusion rate ≥25% showed significantly higher AOFAS score than that with fusion rate < 25% at 12 months. The mean VAS pain score at rest and during weight bearing decreased significantly (p < 0.0001) from operation to six and 12 months.

CONCLUSION: This study demonstrated that β-TCP - NBP is a valuable bone graft substitute for fusion of ankle and hindfoot due to debilitating osteoarthritis and offers an alternative for autograft.

LEVEL OF EVIDENCE: Level II.

PMID:39903260 | DOI:10.1007/s00264-025-06429-z

Association of ulnar variance with primary distal radio-ulnar joint arthritis: a matched case-control study

Int Orthop. 2025 Feb 4. doi: 10.1007/s00264-025-06421-7. Online ahead of print.

ABSTRACT

PURPOSE: Knowledge regarding risk factors for primary distal radioulnar joint (DRUJ) arthritis is limited. This study evaluated the association between ulnar variance (UV) and the development of primary DRUJ arthritis in a matched case-control cohort.

METHODS: Patients with symptomatic DRUJ arthritis were identified from those attending an orthopaedic outpatient clinic between January 2017 and April 2023. The control group comprised individuals without radiographic evidence of DRUJ arthritis. Propensity score matching was performed, aiming for a 1:3 ratio with an age difference limit of five years or less. UV and grade of DRUJ arthritis were assessed using a previously described method. Differences in UV between the case and control groups, and the association between ulnocarpal joint (UCJ) and DRUJ arthritis, were analysed. Receiver operating characteristic (ROC) analysis was used to determine the UV cut-off value for predicting symptomatic DRUJ arthritis.

RESULTS: The case group comprised 49 wrists from 44 patients, while the control group included 147 wrists from 132 individuals. The mean ages of the case and control groups were 69.6 and 67.5 years, respectively. UV was significantly higher in the case group (3.5 ± 2.9 vs. 1.6 ± 1.5 mm). The prevalence of UCJ arthritis increased with higher DRUJ arthritis grades. ROC curve analysis revealed a UV cut-off of 2.9 mm, with a sensitivity of 0.612 and specificity of 0.816.

CONCLUSIONS: A UV greater than 2.9 mm was associated with symptomatic primary DRUJ arthritis. Patients with more advanced DRUJ arthritis were also more likely to have concomitant UCJ arthritis.

PMID:39903259 | DOI:10.1007/s00264-025-06421-7

Comparison of Hemiarthroplasty, total hip arthroplasty, and internal fixation for hip fractures in patients over eighty years of age: factors affecting mortality: a nationwide cohort study of fifty three thousand, four hundred and ninety five patients...

Int Orthop. 2025 Feb 4. doi: 10.1007/s00264-025-06412-8. Online ahead of print.

ABSTRACT

PURPOSE: Hip fractures are a common cause of mortality in elderly patients. This study aimed to determine the predictive factors affecting mortality among patients over the age of 80 who underwent surgical treatment for hip fractures.

METHODS: We searched the Turkish Ministry of Health's e-health database to identify patients over 80 years old who had undergone surgery for proximal femoral fractures from 2016 to 2022. This process yielded 53,495 patients. Demographic data as well as comorbidities, blood transfusions, postoperative 90 days medical complications, and mortality was investigated. Multivariate logistic regression analysis was performed to identify risk factors for one year mortality in patients undergoing surgical treatment for proximal hip fractures.

RESULTS: The mortality rate was 37.2% in the first year. The mean Charlson comorbidity index(CCI) was 6.8 (range: 4-22). In the postoperative period, 68.6% of the patients received blood transfusions. Logistic regression analysis identified significant predictors of one-year mortality in surgical patients, including male gender, increased age, higher CCI scores, AKI, PE, pneumonia, electrolyte imbalance, gastrointestinal bleeding, blood transfusion, and increased mortality risks with hemiarthroplasty and internal fixation compared to total hip arthroplasty. (p < 0.001 for all).

CONCLUSIONS: This large cohort study demonstrated that the mortality rate is high and that the type of surgery, male gender, older age, blood transfusion requirements, and high CCI score are associated with mortality in patients over 80 years of age who have undergone surgery for hip fractures. Preoperative optimization and postoperative care are critical for these vulnerable elderly patients.

PMID:39903258 | DOI:10.1007/s00264-025-06412-8

The emerging field of ultrasound-guided nerve decompression surgery: a narrative review

Int Orthop. 2025 Feb 3. doi: 10.1007/s00264-025-06418-2. Online ahead of print.

ABSTRACT

INTRODUCTION: The development of high-frequency ultrasound technology has transformed musculoskeletal diagnostic practices, offering detailed, multi-plane visualization of superficial structures with remarkable precision and comfort. This non-invasive, pain-free modality is particularly suited for patients of all ages, including children.

PURPOSE: Ultrasound serves as a valuable adjunct to clinical evaluations by facilitating the identification of conditions such as tumours, tenosynovitis, fractures, and nerve entrapments. Portable ultrasound devices have further expanded its utility to clinical, surgical, and emergency settings. Dynamic assessments, such as nerve gliding and entrapment detection, benefit from its precision, enabling targeted therapeutic interventions with minimal risks.

METHOD: The integration of ultrasound into surgical techniques, termed ultrasonosurgery, allows for minimally invasive management of conditions like carpal tunnel syndrome and other nerve compressions. By leveraging high-resolution imaging, these procedures can be performed under local anaesthesia, minimizing traditional surgical complications.

RESULT: This innovative approach aligns with contemporary healthcare trends emphasizing wide-awake surgeries, office-based care, mini-invasive procedures, and technological advancements. Such practices not only streamline patient care but also reduce costs and improve outcomes.

PMID:39900668 | DOI:10.1007/s00264-025-06418-2

Comparison of locking plate and conservative treatment in elderly patients with displaced proximal humerus fractures

Int Orthop. 2025 Feb 3. doi: 10.1007/s00264-025-06425-3. Online ahead of print.

ABSTRACT

PURPOSE: This study aimed to compare the outcomes of conservative treatment and locking plate osteosynthesis in displaced proximal humerus fractures in elderly patients.

METHODS: The study included patients over the age of 60 who were admitted to a tertiary trauma centre between 2020 and 2023, all diagnosed with 2-, 3-, or 4-part proximal humerus fractures. A total of 45 patients underwent either conservative management or locking plate fixation. In the older cohort, patients with Neer Type 2-4 fractures were treated conservatively using Velpeau immobilization. Displaced fractures, specifically 3- and 4-part fractures per the Neer classification, were treated surgically with locking plate fixation. Functional outcomes were evaluated using the Constant Shoulder score, the Disabilities of the Arm, Shoulder, and Hand (DASH) score, and the American Shoulder and Elbow Surgeons (ASES) score, with a minimum follow-up period of one year. Radiographic assessment focused on varus collapse, medial cortex displacement, greater tubercle displacement, absence of fracture lines, and callus formation. Complications, including nonunion, malunion, and avascular necrosis, were also recorded.

RESULTS: Of the 45 patients, 22 underwent locking plate fixation (Group A), while 23 were managed conservatively (Group B). In terms of fracture type, 20 patients were classified as Neer Type 2, 23 as Neer Type 3, and 2 as Neer Type 4. The mean patient age was 73.38 years. Functional scores (DASH, ASES, and Constant) were similar between the two groups, and no significant differences were observed in radiographic parameters. However, complications were significantly more frequent in the locking plate group compared to the conservative group. Two patients who underwent surgery experienced nonunion at the humeral neck. Additionally, secondary surgery was required in one patient due to postoperative infection and in another due to screw penetration into the joint. While no correlation was found between humeral neck malunions and functional outcomes, a negative correlation was observed between tubercle malunions and functional scores.

CONCLUSION: In elderly patients with proximal humerus fractures, no significant differences in functional outcomes were observed between locking plate fixation and conservative treatment. However, locking plate fixation was associated with a higher incidence of complications and secondary surgeries. Thus, it appears that locking plate fixation does not offer superior outcomes compared to conservative management in this patient population.

PMID:39899082 | DOI:10.1007/s00264-025-06425-3

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